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September 15, Vol. 31, No. 16

  • Feature Articles

    • Sample Integrity in Biobanking
    • Josh P. Roberts
    • The need to preserve biological material—whether as a reference archive, a repository for future research, for potential therapeutic use, or as the basis of ongoing drug discovery or production—seems to be growing at an exponential pace... more »
    • New Products Launched at ELA
    • Many companies exhibiting at the “European Laboratory Automation” (ELA) congress were hesitant to make major announcements or unveil new products at a new conference taking place right on the heels of “BIO2011” Nonetheless, several new offerings caught GEN’s eye... more »
    • Expression System Gains Lead to High Protein Yie...
    • Eric S. Langer
    • Continued improvements in recombinant protein expression yields have helped ease production capacity constraints, leading to an apparently healthy and manageable increase in idle capacity According to BioPlan Associate’s 8th annual survey of biopharmaceutical manufacturers, the overall average yield reported for ... more »
    • GEN's 30th Anniversary: Scotland
    • Biotechnology parks have become ubiquitous Over the past 25 years they have sprung up all over the world Countries, states, provinces, and cities seek to put their local life science expertise on display while promoting potential job opportunities as each ... more »
    • U.S. Stem Cell Firms Partnering Overseas
    • Alex Philippidis
    • American companies focused on stem cell treatments and technology platforms have met with success in finding partnerships and revenues overseas in the past decade And it’s not for the reason many people might think, namely the controversy over US federal ... more »
    • Injecting New Life into Cell-Based Assays
    • Kathy Liszewski
    • Cell-based assays continue to provide powerful tools to fuel drug discovery However, costly late-stage failures are driving the industry’s search for improved approaches and novel tools for interrogating cells Throughput, reliability, cost, and physiologic relevance of cellular models for predictive ... more »
    • 3-D Cell Culture Takes Research Deeper
    • K. John Morrow Jr.
    • In vitro cell culture has been a powerful model for in vivo biological processes However, the majority of studies have been conducted using 2-D culture systems in which cells grow as flat monolayers Two recent symposia—CHI’s “Bioprocessing Summit” and the ... more »
    • Recombinant Protein Expression Advances
    • Richard A. Stein
    • Expressing recombinant proteins is one of the most challenging, but at the same time most important tasks in the life sciences Irrespective of the specific protein and the downstream applications, some of the most significant questions involve identifying the best ... more »
  • Columns

    • Hospital-Acquired Infection Market Rebounds
    • Bruce Carlson
    • Treatment of hospital acquired infections (HAIs) has become an increasing focus of healthcare organizations, governments, and news outlets Infections contracted in hospitals are the fourth largest killer in the US There are approximately 40 million hospital admissions each year, and ... more »
    • Getting Up to Speed on Label-Free Methods
    • Oliver Leven
    • Today, label-free is a frequently applied technology Cellular assays are a major screening application as phenotypic cell changes can be observed without disturbing the native cells Label-free instruments are used more and more with this application, which creates specific challenges ... more »