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March 1, Vol. 31, No. 5

  • Feature Articles

    • GEN's 30th Anniversary: DNA Sequencing
    • With the ongoing interest in the latest iteration of next-gen sequencing, we thought it would be a good time to take a look back at some early developments in the automated diagnostic DNA seqeuncing field Thus, this issue’s article commemorating ... more »
    • Range of NGS Applications Rises Quickly
    • Vicki Glaser
    • In the next-gen sequencing (NGS) arena, the focus over the past several years has been on technological advances, moving from second-generation to third-generation sequencing strategies and producing research instruments capable of delivering whole-genome sequences in parallel at increasing speed More ... more »
    • Getting Up to Speed with Modern LC-MS
    • Josh P. Roberts
    • This isn’t your advisor’s LC-MS It’s faster, more specific, more sensitive, more reliable, more automatable It’s the go-to instrumentation of choice for bioanalysis and drug discovery Yet, more sophisticated instrumentation brings with it more challenges, and leaves you to struggle ... more »
    • Strategies to Advance mAb Production
    • K. John Morrow Jr.
    • While approval of new therapeutic antibodies has not progressed as rapidly as was forecast 10 years ago, new products are moving through the pipeline As always, bioprocessing, critical to antibody manufacture, is a key factor in the cost and efficiency ... more »
    • CMOs Seek "the" Competitive Edge
    • Gail Dutton
    • Contract manufacturers are embracing new uses of established techniques to give them an edge in an increasingly competitive environment, according to companies exhibiting at the “Interphex” conference later this month in New York City Examples of such practices include lyophilization, ... more »
    • Demand for High-Tech Outsourcing Growing
    • Eric S. Langer
    • Outsourcing can allow companies to focus on their core competencies Until recently, however, outsourcing has tended to involve lower end, repetitive tasks Today, outsourcing shows clear signs of integrating into much higher end, technical activities... more »