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February 15, Vol. 25, No. 4

  • Feature Articles

    • Personalized Arthritis Therapy
    • Recent reports of an increased risk of heart attack with the Cox-2 inhibiting drugs Vioxx and Celebrex have resulted in a huge setback for arthritis therapeutics These drugs had become staples for the treatment of osteoarthritis (OA) and rheumatoid arthritis, ... more »
    • What it Costs fo Operate a Biotech Facility
    • A new corporate location study compares the cost of doing business for the biotechnology industry in a series of 50 US, Canadian, and European cities The study, prepared by the Princeton, NJ-based site selection firm, The Boyd Co, focuses on ... more »
    • Staying Up-to-Date in Biomarker Research
    • Costs associated with populating the drug pipeline are, as always, on the rise Success demands that pharmaceutical research be linked to the biology of the human system as closely as possible and as soon as possible in the candidate-selection process... more »
    • Is Biotechnology Complacent to PAT Principles?
    • Gail Dutton
    • Since the FDA released its final guidance on process analytical technology (PAT) last autumn, there's been a flurry of conference activity focusing upon implementation If the lists of speakers are any indication, however, the activity is almost exclusively coming from ... more »
  • Columns

    • FDA's Draft Guidance on Pharmacogenomics
    • Pharmacogenomics is said to have been created with the 1955 presentation of re-search relating excretory levels of isoniazid to therapeutic results (Frueh & Gurwitz; 2004) In the fifty years since then, the number of published articles referencing pharmacogenomics or pharmacogenetics ... more »
    • Conservative Outlook Seen at Investor Forum
    • Biotech investors, executives, and entrepreneurs have always made it a priority to gather at the beginning of each year in San Francisco to conduct business at the “JP Morgan Healthcare Conference,” formerly the “Hambrecht & Quist Life Science Investment Conference” ... more »