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November 1, Vol. 30, No. 19

  • Feature Articles

    • Exploiting HDAC Inhibition
    • Kathy Liszewski
    • Histone deacetylases (HDACs) are emerging as exciting new targets for drug development, particularly for cancer and metabolic diseases Because they exert control over gene transcription and cell-cycle progression, they represent a novel approach for epigenetic therapeutic intervention... more »
    • Spain Bolsters Biotech in Southern Europe
    • Gail Dutton
    • A functional therapeutic that reduces both blood cholesterol and ingested cholesterol was introduced by AB-Biotics  at last month’s “BioSpain” conference in Pamplona Called AB-Life, this probiotic therapy reduced these two types of cholesterol by 14%, according to Miquel Àngel Bonachera, ... more »
    • SAFC Expands to Meet Customer Demands
    • K. John Morrow Jr.
    • Suppliers to the biotechnology market, like Sigma-Aldrich’s SAFC division, are kept on their toes by constantly evolving customer demands As a result, vendors have built larger and larger catalogs of products, moving into complex and challenging areas over the years... more »
    • Microarray Technology Moves to the Fore
    • K. John Morrow Jr.
    • Microarray technology has come of age as a powerful approach to revealing the genome and its dynamic expression through the application of gene-hybridization or gene-expression microarrays While the former are aimed at detecting the presence of specific genes in a ... more »
    • Disposable Bioreactors Enter Mainstream
    • Angelo DePalma, Ph.D.
    • Disposable bioreactors have become the vanguard of single-use processing, a litmus test of sorts for the acceptance of single-use equipment in biomanufacturing Adoption has been slower than expected, but progress has been encouraging nonetheless The steady uptake of disposables in ... more »