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August 1, Vol. 30, No. 14

  • Feature Articles

    • Use of Ultrahigh Pressure on the Rise
    • K. John Morrow Jr.
    • Over the course of his distinguished career, Nobel Prize winner Percy Bridgman, PhD, investigated the behavior of materials under elevated hydrostatic pressure These studies, for which he designed his own high-pressure equipment, included the thermodynamic effect of pressure on proteins ... more »
    • Gene-Expression Profiling Goes Solo
    • Nina Flanagan
    • As technology continues to evolve, the potential of gene-expression profiling continues to grow The field is now expanding to focus on single cells, which many believe have unlimited potential for molecular biologists A number of companies and academicians presented their ... more »
    • Strategies for Successful Process Scale-Up
    • Susan Aldridge, Ph.D.
    • Scaling up biologics production from the bench to clinical and commercial scale is a central consideration of process design and development Issues, challenges, and new technologies in scale-up were all discussed at  “BioProcess International Europe” held in Vienna recently The ... more »
    • Disposable & Reusable Manufacturing Trends
    • Vicki Glaser
    • Demand for single-use, disposable technology for unit operations such as buffer and media preparation, seed culture production, and virus inactivation, as well as for process development and manufacturing for both cell culture and microbial fermentation continues to increase Mike Sattan, ... more »
    • Integrating Methods for mAb Production
    • Angelo DePalma, Ph.D.
    • Scientists working in the bioprocess arena have a lot on their plates lately, including choosing between single-use and stainless steel equipment, integrating processes and instruments, and improving resource and facility utilization Tool companies are scrambling to do their part to ... more »
    • BD Biosciences Opens New Miami Facility
    • A new cell culture media and supplement production facility will be opened by BD Biosciences in Miami-Dade County this month The building was designed to support a number of advanced technologies and operating procedures... more »
    • Emerging Issues in Informed Consent
    • Jacqueline Klosek
    • Controversies concerning the meaning of informed consent in connection with the use of genetic materials from human subjects are not new Recent legal disputes are, however, bringing the matter to the forefront once again and raising important questions about whether ... more »