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July 1, Vol. 29, No. 13

  • Feature Articles

    • Building a Successful Biotech Incubator
    • Gail Dutton
    • Regions are looking to biotech to make the difference between boom and bust for their economies, but it takes more than tax incentives, buildings, and land to construct a winning biotech incubator Unfortunately, the regions doing the planning often ignore ... more »
    • Upgrading Cell-Based Viability Assays
    • K. John Morrow Jr.
    • Pharmas and biotechs struggle to screen large quantities of compounds, hoping to eliminate early those that would prove more destructive than beneficial One avenue toward a successful resolution of this challenge is the cell-based viability assay, a rapid and convenient ... more »
    • Meeting Biomagnetic Separation Needs
    • Gail Dutton
    • Researchers’ needs are driving advances in the biomagnetic separations market Recognizing that binding capacity is one of the key criteria scientists use when choosing particles, Thermo Scientific launched SeraMag® SpeedBead™ streptavidin-blocked particles this month This bead offers many of the ... more »
    • High-End Mass Spec Systems Introduced
    • Vicki Glaser
    • At the ASMS conference held last month in Philadelphia, Waters launched the Synapt™ G2 quadrupole TOF-MS system, which incorporates QuanToF™ and High Definition MS™ technologies and is designed for use with Waters’ Acquity UPLC-MS and MS/MS applications... more »
    • Competition Mounting in Peptide Market
    • Vicki Glaser
    • Advances in synthetic chemistry, solid support materials, purification technology, and biological drug delivery strategies have all contributed to strong growth and expanding interest in peptide drugs, especially among large pharma companies Even with the global economic downturn, the market for ... more »
    • European Overview: Firms Look for Niche in Pepti...
    • Sophia Fox
    • In May, TheraCode acquired JPT Peptide Technologies, a wholly owned subsidiary of Jerini JPT offers peptide-based products and services for vaccine development, immune monitoring, and peptide biomarker discovery “Our acquisition by TheraCode means that, in addition to continuing our work ... more »
    • Getting Real with Downstream Processing
    • Angelo DePalma, Ph.D.
    • Like all areas of bioprocessing, downstream purification has its own favored buzzwords—titers, bottlenecks, capacity, and others—meant to evoke a particular response depending on who is speaking or writing them But, if we could just identify one leading, universal trend in ... more »
    • Getting the Most out of Quantitative PCR
    • Catherine Shaffer
    • The enhancement of PCR with real-time quantitative methods takes PCR from a workhorse laboratory preparatory method for molecular biology to an extremely powerful diagnostic and analysis tool for clinical and research applications Studies of gene expression are some of the ... more »
    • Choosing a Clinical Trial Disclosure System
    • Satish Tadikonda
    • New and evolving laws, mandates, and guidance from regulatory bodies and international health organizations necessitate that all companies performing clinical trials provide increased transparency They must do this through specific disclosure processes detailing their clinical trial procedures, results, and, soon, ... more »
  • Tutorials

    • Fluidics-Free Molecular Interactions Analysis
    • Krista Witte
    • Molecular interactions play a myriad of important roles in drug discovery and development From determining mechanism of action to identifying unwanted biological reactions (eg, monitoring for an immune response to an administered drug), the study of binding events is a ... more »
    • Automating Magnetic Bead Multiplex Assays
    • Jason Greene
    • Enzyme-linked immunosorbent assays (ELISAs) continue to evolve to meet increased user demands One such advancement stemming from traditional ELISA technology is the use of microspheres (beads) as a solid support matrix in conjunction with microplates Bead-based microplate assays provide greater ... more »