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June 15, Vol. 37, No. 12
  • Feature Articles

    • Moving Microfluidics to the Big Time
    • Vivienne Raper
    • The market for microfluidics has experienced tremendous growth over the past few years Lab-on-a-chip devices for use at the point of care are allowing faster and more portable testing Other microfluidic devices, for controlling and manipulating sub-microliter volumes of liquid ... more »
    • Synthetic Biology Expands and Grows
    • Kate Marusina
    • Synthetic biology is an exciting and rapidly evolving field of research that can broadly be defined as the design (or redesign) and construction of novel artificial biological pathways, organisms, or devices Applying engineering principles to biological components allows us to ... more »
    • Targeting Progenitor Cells to Regenerate Damaged...
    • Vicki Glaser
    • The promise of cell therapy for regenerative medicine is often viewed as being synonymous with stem cell therapy, but some companies are instead successfully bringing progenitor cell-based cell therapy approaches through preclinical and clinical development They are targeting disorders that ... more »
    • Opening Up Relieves Downstream Bottlenecks
    • The first step in solving a problem is admitting there is one So, let’s put aside the idea that a downstream bottleneck isn’t a real problem, but just a matter of perception—specifically, a way of perceiving a capacity mismatch This ... more »
  • Tutorials

    • High-Definition Immunology
    • Brian Fritz
    • The biology of adaptive immunity plays an important part in understanding human health and disease A deeper understanding of the adaptive immune repertoire, especially of paired T-cell receptor (TCR) alpha and beta chain genes, will enable researchers to more accurately ... more »
    • Validating a Point-of-Use Leak Test
    • Marc Hogreve
      Nick Hutchinson
    • Single-use bioreactors have been successfully implemented by the biopharmaceutical industry up to the 2,000-L scale The performance of single-use bioreactors is comparable if not superior to stainless-steel alternatives, even in the most demanding applications such as continuous cell culture (Sherman ... more »