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Jun 2, 2014

Targeting the Tumor Microenvironment

Humanizing mouse models of cancer to expand drug development opportunities.

Targeting the Tumor Microenvironment

Patient-derived xenograft tumor (PDX) models can provide a more relevant heterogeneous system in which human tumor and stromal cells are in close cooperation within a unique microenvironment. [© vitanovski - Fotolia.com]

  • Introduction

    The majority of cancer drugs entering Phase I clinical studies fail to reach the market. The success rate in predicting clinical efficacy of anticancer ...

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