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April 29, 2014

The Utility of Fat for Regenerative Medicine

The adipose tissue field is translating from plastic surgery to possible regenerative purposes.

The Utility of Fat for Regenerative Medicine

Fat’s mechanism of action is unclear at present, but the clinical results to date cannot be ignored.

  • This report represents our continuing coverage of the potential utilization of adipose tissue and its associated components (such as the stem cells contained therein) as a means for mediating regenerative medicine.

    Highlights of this report:

    • The current use of fat for cosmetic and reconstructive purposes provides the raison d’être for its deployment for regenerative medicine/cellular therapy.
    • More work remains to identify the component[s] within adipose tissue responsible for its regenerative properties—Is it the cells? The scaffold? The cytokine milieu? Much is unclear at present.
    • These results lend credibility to the notion that early clinical results could provide a good rationale for deeper investigations for mechanism of action; the case here demonstrates that clinicians utilizing adipose-derived cells as a means for addressing musculoskeletal and other conditions provide a good foundation for exploring the regenerative potential of this tissue.

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