Leading the Way in Life Science Technologies

GEN Exclusives

More »

GEN Exclusives

More »

For full access to this article login to GEN Select now.

Jul 31, 2014

Golgi—A Potential Drug Target for Alzheimer's Disease

In this literature review, the authors show how accumulation of amyloid beta peptides leads to Golgi fragmentation.

Golgi—A Potential Drug Target for Alzheimer's Disease

Golgi fragmentation in AD is caused by phosphorylation of Golgi structural proteins, which is induced by Aβ-triggered cyclin-dependent kinase-5 activation. [© psdesign1 - Fotolia.com]

  • First described in 1906 by Alois Alzheimer, Alzheimer's disease (AD) represents the most common form of dementia today and the sixth leading cause of ...

Not registered yet? Please fill out the form below and enjoy complimentary access to this and an exclusive collection of premium content and personalization features as a GEN Select insider. Learn More.

Get GEN Select Access Now

    • Do not put any letters or characters here if you are not a spy program.
    •  


Be sure to take the GEN Poll

Drug Price Hikes

Novum Pharma recently raised the price of an acne cream by over 3,900% in less than a year-and-a-half and Mylan increased price of EpiPen from $100 to $608 . Do you think pharmaceutical companies need to be subjected to price controls?

More »