Presents an Educational and Informative Audio Webinar
Advances in the
Analysis of Glycans for
the Characterization
of Biopharmaceuticals
Original Broadcast Date: Tuesday, June 23, 2009
Many protein-based biopharmaceuticals are glycosylated proteins. The glycans themselves directly affect the efficacy and safety of the biopharmaceutical. Measurements of the sites of glycan attachment, the glycans that are present, and the relative proportions of each alternative structure are required for both pharmaceutical and regulatory reasons. The number and similarity of possible structures of these molecules place tremendous demands on the analytical techniques. Recent advances in chromatographic approaches have led to better resolution, sensitivity, and speed for greater reliability in the qualitative and quantitative analysis of protein glycosylation.
Researchers involved in protein characterization will therefore want to attend Advances in the Analysis of Glycans for the Characterization of Biopharmaceuticals, a free webinar conducted by world-class protein scientists and hosted by Genetic Engineering & Biotechnology News.
Who should attend?
By focusing on liquid chromatography (LC) methodology as applied to glycan analysis, this webinar will be advantageous for:
- Biochemists who identify and characterize biotherapeutic proteins
- Discovery scientists analyzing post-translational modifications of proteins
- Development scientists involved in process optimization of cultures
- Pharmaceutical chemists who develop formulations and test stability
- Quality control chemists monitoring biopharmaceuticals for quality and consistency
- Developers of follow-on biologics
Key learning points for this webinar include:
- Role of glycan analysis in characterizing modern biotherapeutics
- Introduction of the application of UltraPerformance LC® (UPLC®)
- The mechanism and principles of UPLC separations for glycan structures
- The application of UPLC glycan analysis in a biopharmaceutical characterization laboratory
Your host for this webinar will be John Sterling, Editor in Chief of GEN. Panelists include Pauline Rudd, Ph.D., Professor of Glycobiology, University College Dublin; Jonathan Bones, Ph.D., Dublin Oxford Glycobiology, Conway Institute, University College Dublin; Jihong Wang, Ph.D., Senior Scientist, Analytical Biochemistry, MedImmune; Thomas E. Wheat, Ph.D., Principal Scientist and Life Science Laboratory Manager, Waters Corporation.
A live Q&A session will follow the presentations, offering you a chance to pose questions to our expert panelists.
Available for On-Demand Viewing!
PANELISTS
|
Pauline Rudd, Ph.D. |
|
Jonathan Bones, Ph.D. |
|
Jihong Wang, Ph.D. |
|
Thomas E. Wheat, Ph.D |
MODERATOR
|
John Sterling |
Produced with support from
