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Significant progress is being made toward the development of an effective HIV-AIDS vaccine. In autumn 2009, a collaborative effort between the Ministry of Health in Thailand, the U.S. Military, and the U.S. National Institute of Allergy and Infectious Disease announced the first encouraging results from an efficacy trial—31% prevention of infection in a 16,402-person community-based trial in Thailand. With this encouraging news in the background, several companies are working toward an AIDS vaccine. So, when do you think one will be approved in the U.S.?