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Nutrigenomics is a rapidly growing discipline that focuses on identifying the genetic factors that influence the body’s response to diet and studies how the bioactive constituents of food affect gene expression. A key goal is the development of personalized diets for disease prevention.
During this week's podcast Drs. Eugene Kolker and Vural Ozdemir note that nutrigenomics' bidirectional approach to investigating how the genetic traits of an individual or population interact with diet offers many possibilities for targeted clinical interventions and preventive medicine. These may include either modifying diet or the biochemical response to food exposure to prevent disease in individuals shown to be susceptible to the consequences of unfavorable dietary/genomic interactions.
In the future, nutrigenomics may potentially help guide the development of customized diets based on an individual's genetic makeup, the two scientists point out.
Nutrigenomics and personalized diets for the prevention of disease was the subject of two special issues of OMICS: A Journal of Integrative Biology. Part 1 appeared in Volume 12, Number 4, December 2008, and Part II was published in Volume 13, Number 1, February 2009. For more information see www.liebertonline.com.
Eugene Kolker, Ph.D. is Chief Data Officer at Seattle Children's Hospital and Head of the Bioinformatics & High-Throughput Analysis Laboratory at Seattle Children's Research Institute. He is also Editor in Chief of OMICS: A Journal of Integrative Biology, published by Mary Ann Liebert, Inc.
Vural Ozdemir, M.D., Ph.D. is Research Assistant Professor in Bioethics in the Department of Social and Preventive Medicine and Faculty of Medicine at the University of Montreal. He is also Associate Editor of OMICS.