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GEN’s editor in chief, John Sterling, interviews life science academic and biotech industry leaders on important research, technology, and trends. These podcasts will keep you informed with all the important details you need.

RESEARCHERS CREATE BEATING HEART IN THE LABORATORY

1/24/2008

- Interview with Doris Taylor, Ph.D., Director of the University of Minnesota Center for Cardiovascular Repair and Medtronic Bakken Professor of Medicine and Physiology

University of Minnesota scientists have created a beating heart in the laboratory.

During this week's GEN podcast, Dr. Doris Taylor, principal investigator of the research, provides the main details of the experiment and talks about the long-term goals of this work. The experiment relied on a process called whole organ decellularization, which Dr. Taylor describes.

Her team's study involved immature rat heart cells but Dr. Taylor looks at the potential of using human stem cells to build a new heart. She also explains why the decellularization approach is already changing the way researchers think about engineering organs other than the heart.

Listen to the podcast then return to the blog to give your thoughts on the following question:

What additional work do you think needs to be done from a tissue engineering point of view to move Dr. Taylor’s beating heart experiment forward and eventually into the clinic?

Or, if you prefer, post your own topic on the biotech industry subject of your choice. Please share your opinions and observations.

As the Medtronic-Bakken Chair in Cardiac Repair and the Director of the Center for Cardiovascular Repair, Dr. Taylor blends research using stem cells, genes, and devices to develop novel cardiac and vascular technologies--ones to prevent, treat, and hopefully one day, cure heart ailments. She is involved in both laboratory and clinical studies using cell therapy to treat disease.

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