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GEN’s editor in chief, John Sterling, interviews life science academic and biotech industry leaders on important research, technology, and trends. These podcasts will keep you informed with all the important details you need.
Scientists at the Department of Energy's Lawrence Berkeley National Laboratory and the Scripps Research Institute say they have solved the essential structure of the XPD protein. XPD is one component of an essential repair mechanism that maintains the integrity of DNA. The research was published in the May 30 issue of Cell.
During this week's GEN podcast, Dr. Jill Fuss, one of paper's authors, discusses why XPD is such an important molecule and why solving its structure is so significant. She explains how XPD carries out its role as a DNA repair protein and how the research team went about finding the XPD gene and then crystallizing it. Dr. Fuss also talks about future plans to build on this research and to advance medicine's ability to deal with cancer and the problems associated with aging.
Jill Fuss, Ph.D. is a project scientist in biochemistry in the laboratories of Priscilla K. Cooper and John A. Tainer at Lawrence Berkeley National Laboratory, where she also did her postdoctoral work. After earning a B.A. in environmental science at Wesleyan University in Connecticut, Jill switched fields to study molecular and cell biology. She received her Ph.D. in 2001 from the University of California, Berkeley. Jill was the recipient of a National Institutes of Health Ruth L. Kirschstein National Research Service Award and was named a Department of Energy Outstanding Mentor.