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GEN’s editor in chief, John Sterling, interviews life science academic and biotech industry leaders on important research, technology, and trends. These podcasts will keep you informed with all the important details you need.

A novel invention developed by a New York Institute of Technology scientist could revolutionize biological and clinical research and may lead to treatments for cancer, AIDS, Alzheimer's, diabetes, and genetic and infectious diseases. Dr. Claude Gagna and his team discovered how to immobilize intact double-stranded (ds-), multi-stranded or alternative DNA and RNA on one microarray. This immobilization allows scientists to duplicate the environment of a cell, and study, examine and experiment with human, bacterial and viral genes. This invention provides the methodology to analyze more than 150,000 non-denatured genes.



During this week's podcast, Dr. Gagna talks about why his nucleic acid microarray is so novel and how it will allow scientists to carry out research differently. He also explains how this new type of microarray will assist biotech and pharmaceutical companies in new drug discovery and development. In addition, Dr. Gagna provides details on two recently developed techniques in his lab, transitional structural chemogenomics and transitional structural chemoproteomics, and on what impact these methods will have on life science R&D.



Listen to the podcast about this potentially revolutionary invention. Then return to the blog to give your thoughts on the following question:


What other practical applications might be possible with Dr.Gagna's new nucleic acid microarray?



Or, if you prefer, post your own topic on the biotech industry subject of your choice. Please share your opinions and observations.
Claude Gagna, Ph.D., is an Associate Professor in the Department of life Sciences, School of Health Professionals, Behavioral and Life Sciences, at the New York Institute of Technology in Old Westbury, NY. He received a Ph.D. Degree in Anatomy, with a minor in Biochemistry, from New York University. He won postdoctoral fellowships from the University of Medicine and Dentistry of New Jersey, Medical School, Department of Ophthalmology, and New York University, Basic Medical Sciences, Department of Biochemistry. Last year Dr. Gagna was inducted into The New Jersey Inventors Hall of Fame, which recognizes innovators for advancing the state-of-the-art in their areas of expertise. Dr. Gagna was honored for his invention of novel technology to immobilize unaltered DNA or RNA molecules onto specially modified microscope slides used in basic biological research and drug efficacy testing.


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