GEN Exclusives

More »

GEN Podcasts

*Podcasts play in a pop-up window. Please make sure your pop-up blocker is off.

GEN’s editor in chief, John Sterling, interviews life science academic and biotech industry leaders on important research, technology, and trends. These podcasts will keep you informed with all the important details you need.

Using an RNA-powered nanomotor, University of Cincinnati (UC) biomedical engineering scientists successfully developed an artificial pore able to transmit nanoscale material through a membrane.

In a study led by Dr. Peixuan Guo, members of the UC team inserted the modified core of a nanomotor into a lipid membrane. The resulting channel enabled them to move both single- and double-stranded DNA through the membrane.

During this week's podcast Dr. Guo talks about the creation of the RNA nanomotor and provides additional details on how it was used and on the results that were obtained. He discusses the key differences between the UC team’s single pore construct and other systems and explains the importance of such differences.

Dr. Guo goes on to explore the potential use of the engineered biopore channel and looks at some of the broader applications of the method by which the scientists were able to move DNA through the membrane.
Peixuan Guo, PhD, is the Director of the NIH Nanomedicine Development Center at the University of Cincinnati, one of eight Nanomedicine Development Centers in the country. At UC, he holds the Dane and Mary Louise Miller Endowed Chair in Biomedical Engineering and serves as a professor in the biomedical engineering department. Guo received his PhD in Microbiology & Genetics at the University of Minnesota and completed postdoctoral work in Molecular Virology at New York State Department of Health as well as serving as a visiting scientist at the NIH. Currently, Dr. Guo is a member of the NIH Steering Committee and serves as an editor/editorial board member for four nanotech journals. His research concentrates on nanobiotechnology, specifically RNA nanotechnology.

Add a comment

  • Add a comment

  • Click here to Login/Register for free. You will be taken back to your selected item after Login/Registration.

Related content


GEN Jobs powered by connects you directly to employers in pharma, biotech, and the life sciences. View 40 to 50 fresh job postings daily or search for employment opportunities including those in R&D, clinical research, QA/QC, biomanufacturing, and regulatory affairs.
More »

Be sure to take the GEN Poll

Patient Access to Genetic Information

Do you think patients have the absolute right to gain access to their own genetic information from medical or clinical laboratories?

More »