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GEN’s editorial staff interviews life science academic and biotech industry leaders on important research, technology, and trends. These podcasts will keep you informed with all the important details you need.

Human beings have astonishing genetic vulnerabilities. More than half of us will die from complex diseases that trace directly to those vulnerabilities, and the modern world we’ve created places us at unprecedented risk from them. In It Takes a Genome, published by FT Press, Dr. Greg Gibson posits a revolutionary new hypothesis: Our genome is out of equilibrium, both with itself and its environment. Simply put, our genes aren’t coping well with modern culture.

During this week's podcast, Dr. Gibson explains why our genes are not fairing better in the modern world. He dismisses the concept of a disease gene and details his views on the more complex nature of most human diseases. He defines "molecular existentialism" and reviews some chapters in his book that highlight specific diseases as examples of the clash that results from human genes functioning in modern life.

Dr. Gibson tackles the question that "if natural selection is so efficient, how come the evolutionary process does not remove cancer genes from the gene pool." A self- described empirical evolutionary quantitative geneticist, Dr. Gibson reveals the unique insights gained by his approach to the study of genes and human evolution.
Gregory C. Gibson, Ph.D., is Professor of Genetics at the University of Queensland, Australia and was previously William Neal Reynolds Distinguished Professor of Genetics at North Carolina State University. He is a leader in the emerging field of empirical evolutionary quantitative genomics, which uses genomic approaches to study how genes and the environment interact to produce quantitative variation. He holds a doctorate. from the University of Basel, Switzerland, and did postdoctoral work at Stanford University. With Spencer V. Muse, he co-authored A Primer of Genome Science, one of the field's leading textbooks. His most recent book is entitled It Takes a Genome: How a Clash Between Our Genes and Modern Life Is Making Us Sick, by published by FT Press www.ftpress.com/science.

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