Leading the Way in Life Science Technologies

GEN Exclusives

More »

GEN News Highlights

More »
Sep 21, 2007

VIRxSYS Purchases Intronn Assets

  • VIRxSYS acquired Intronn’s core technology, SMaRT™, and preclinical programs in an all-stock transaction. “Adding the SMaRT™ RNA platform to our lentiviral vector delivery platform will help us build VIRxSYS into the driving force behind the next generation of gene therapy,” states Riku Rautsola, Ph.D., president and CEO of VIRxSYS.

    The spliceosome-mediated RNA trans-splicing technology, or SMaRT, is different from most RNA tools, according to VIRxSYS. Most methods deploy RNA modifications as gene silencers to block selected gene functions. SMaRT on the other hand reprograms gene expression at the RNA level by inserting a new sequence into a gene to repair mutations or change gene expression, the company explains.

    “We see tremendous synergy between our two technologies,” Dr. Rautsola comments. “Combining the VIRxSYS delivery platform with the SMaRT™ RNA reprogramming technology will help us create powerful new therapies more rapidly. Our initial focus will continue to be on HIV and genetic diseases. Intronn brings advanced preclinical programs in hemophilia and cardiovascular disease, which will integrate extremely well with our own programs in those areas, eliminating duplicative cost and effort.”

Be sure to take the GEN Poll

Drug Price Hikes

Novum Pharma recently raised the price of an acne cream by over 3,900% in less than a year-and-a-half and Mylan increased price of EpiPen from $100 to $608 . Do you think pharmaceutical companies need to be subjected to price controls?

More »