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Sep 22, 2009

Unizyme and SARomics Ink Drug Discovery Deal for Inflammatory Diseases

  • Unizyme Laboratories in Denmark and SARomics in Sweden entered a research service collaboration related to inflammatory diseases. The aim is to discover novel lead compounds targeting dipeptidyl peptidase I (DPPI; cathepsin C).

    Unizyme will focus on identifying new small molecules that interact with and inhibit the function of DPPI. SARomics will apply its expertise in structure-based drug design to assist in the development of lead compounds.

    SARomics will also facilitate the interpretation of 3-D structures of DPPI interacting with small molecules provided by Unizyme. This information will be combined with high-speed computational methods, like high-performance ligand-receptor docking, to accelerate lead molecule identification.

     



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Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

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