Leading the Way in Life Science Technologies

GEN Exclusives

More »

GEN News Highlights

More »
May 11, 2010

Swedish Orphan Taps Biomodels to Develop Screening Platform for Oral Mucositis Risk

  • Swedish Orphan Biovitrum and Biomodels are teaming up for a research project that ultimately aims to develop a clinical screening platform to define mucositis risk in patients undergoing conditioning regimens for hematopoietic stem cell transplants (HSCT). The project will be funded by Swedish Orphan, which says the development of assays that enable a personalized medicine approach is an ideal strategic fit with its mission to develop medicines for rare diseases.

    Biomodels has experience with a range of oral mucositis models and has exclusive rights to the hamster models developed at Harvard’s Brigham and Women’s Hospital by Stephen T. Sonis, Biomodels’ CMO, as well as rat and mouse models.

    Oral mucositis is a frequent and debilitating complication of conditioning regimens prior to HSCT. As a result, an assay that could accurately determine which patients will need mucositis intervention associated with HSCT would be a benefit.

    “We are enormously excited to work with Swedish Orphan Biovitrum to apply our novel approach for patients undergoing aggressive cancer therapy,” comments Dr. Sonis. “We are optimistic that as a consequence of this project, patients undergoing HSCT will be able to receive targeted therapies to reduce the burden of these symptoms.”



Related content

Be sure to take the GEN Poll

Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

Do you agree that ecstasy should be studied for its potential therapeutic benefits?

More »