GEN Exclusives

More »

GEN News Highlights

More »
Dec 19, 2007

Sunesis and the Multiple Myeloma Research Consortium to Investigate Firm’s Phase I Candidate

  • The Multiple Myeloma Research Consortium (MMRC) is collaborating with Sunesis Pharmaceuticals to further evaluate the company’s Phase I compound. SNS-032 is currently being tested in patients with multiple myeloma and chronic lymphocytic leukemia.

    The MMRC will investigate the preclinical activity of SNS-032 in multiple myeloma-relevant models and in primary disease tissue. Data from these studies, according to Sunesis, will help identify relevant mechanism-based biomarkers of patient response. The company says that such information may guide rational combination strategies in planned clinical trials of SNS-032 in multiple myeloma.

    SNS-032 is a potent, selective inhibitor of cyclin-dependent kinases 2, 7 and 9 that suppresses both cell cycle progression and transcription. It has reportedly been shown in preclinical and clinical studies to deplete cells of key survival factors including myeloid cell leukemia sequence 1.



Jobs

GEN Jobs powered by HireLifeScience.com connects you directly to employers in pharma, biotech, and the life sciences. View 40 to 50 fresh job postings daily or search for employment opportunities including those in R&D, clinical research, QA/QC, biomanufacturing, and regulatory affairs.
 Searching...

Unable to get Jobs Listings.

More »

GEN Poll

More » Poll Results »

Biosimilars

Compared to the original biologics, do you think biosimilars run the risks of being less effective and causing more side effects?