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May 14, 2007

Stallergenes and CMC Biopharmaceuticals Collaborate to Advance Allergy Drug

  • Stallergenes and CMC Biopharmaceuticals inked an agreement for development and supply of recombinant Bet v 1 (rBet v 1) purified bulk. The product is the protein that embodies most of the allergenicity of birch pollen, according to Stallergenes.

    Scale up the manufacturing of GMP purified recombinant Bet v 1 will be undertaken by CMC Biopharmaceuticals. The company also will produce batches for Phase III trials and commercial supply.

    “This agreement will speed our ORALAIR® Bet v 1 project towards late-stage clinical trials and registration while securing the supply of active ingredients for commercial batches,” remarks Albert Saporta, chairman and CEO of Stallergenes.

    Stallergenes reports that it has carried out a proof-of-concept trial aimed at demonstrating the ability of Bet v 1 to reduce the symptoms in patients allergic to birch pollen. This double-blind, placebo-controlled study conducted in 150 patients in five countries was highly significant in efficacy and has also shown a good safety profile in the rBet v 1 group versus placebo, similar to the natural extract group, says the firm.

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Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

Do you agree that ecstasy should be studied for its potential therapeutic benefits?

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