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Oct 24, 2006

Schering-Plough Contracts with OncoMethylome Sciences for Use of MGMT Methylation Testing

  • OncoMethylome Sciences will provide further MGMT methylation testing to Schering-Plough, according to a new nonexclusive service agreement. The MGMT gene is a biomarker that has been shown to be methylated in a number of cancer types. OncoMethylome owns a patent-protected assay for determining the methylation status of the MGMT gene.

    Under the terms of this agreement, OncoMethylome’s assay will be used for MGMT methylation testing in multiple national and international clinical trials involving temozolomide in brain cancer and other cancers. In addition, OncoMethylome will receive processing fees for providing Schering-Plough with testing services in connection with clinical trials focused on brain cancer as well as other cancers.

    OncoMethylome currently provides its services for a multicenter clinical trial that is supported by Schering-Plough. The trial evaluates whether patients with glioblastoma multiforme can benefit from a more intensive temozolomide drug treatment regimen. MGMT methylation is being tested in this study for all patients’ tumors.



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Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

Do you agree that ecstasy should be studied for its potential therapeutic benefits?

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