GEN Exclusives

More »

GEN News Highlights

More »
Feb 2, 2009

Researchers Figure Out that Too Much Lamin Leads to Myelin Failure

  • A group of scientists at the University of California have found that while the protein lamin is necessary in the initial stages of myelin formation, too much lamin promotes myelin breakdown.

    The investigators also discovered a signal that fine-tunes lamin expression. The miR-23signal turned down lamin gene expression, preventing demyelination due to lamin overexpression. This kept the myelin sheaths around nerve cells functional, properly insulating the cells.

    The report will be published in the March/April issue of Disease Models & Mechanisms.

    ---

     



Related content

Jobs

GEN Jobs powered by HireLifeScience.com connects you directly to employers in pharma, biotech, and the life sciences. View 40 to 50 fresh job postings daily or search for employment opportunities including those in R&D, clinical research, QA/QC, biomanufacturing, and regulatory affairs.
 Searching...
More »

Be sure to take the GEN Poll

Fear or Encouragement?

To change public attitudes about dealing with health issues do you agree that the public officials should rely on fear and disgust instead of encouraging and promoting healthy behaviors?

More »