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Mar 11, 2008

Proteros and OSI Broaden Existing Protein Crystallography Collaboration

  • Proteros biostructures and OSI Pharmaceuticals have expanded their protein crystallography partnership for the fifth time. Proteros will now also provide Gene-to-Structure services.

    The extension follows the successful delivery of high-resolution protein-ligand structures on multiple kinase targets under Proteros' Gallery Structure mode with compounds supplied by OSI, the company’s report. 

    The master service agreement, signed in October 2007, calls for Proteros to utilize its capabilities in construct design, protein expression and purification, as well as protein-structure determination to deliver a de novo protein structure and protein-ligand structures on a challenging kinase target.



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Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

Do you agree that ecstasy should be studied for its potential therapeutic benefits?

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