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Mar 16, 2010

Pfizer to Assess Tekmira Technology to Deliver siRNAs in Preclinical Models

  • Tekmira and Pfizer will collaborate on evaluating Tekmira's stable nucleic acid-lipid particle (SNALP) technology to deliver siRNA molecules provided by Pfizer. Tekmira will be responsible for preparing the SNALP formulations, and Pfizer will evaluate the formulations in preclinical models.

    SNALP technology encapsulates siRNAs in uniform lipid nanoparticles, which are effective in delivering RNAi therapeutics to disease sites in preclinical models, according to Tekmira. SNALP formulations are manufactured by a proprietary method that is robust, scalable, and highly reproducible, the firm adds.



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Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

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