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May 1, 2008

Pfizer Spins Out Esperion with a $22.75M Series A Financing

  • Pfizer has decided to sell one of its research divisions, Esperion Therapeutics, to an enterprise funded by a syndicate of investors. Esperion also reports that it has completed a $22.75 million series A tranche financing.

    As part of the spinout, Esperion will take with it a small molecule dual inhibitor of fatty acid and cholesterol synthesis for the treatment of dyslipidemias. Pfizer discontiuned research on this compound while still in early preclinical development, according to Rick Anderson, Pfizer spokesman.

    The firm will focus R&D activities on the cardiovascular and metabolic disease space. Pfizer retains selected programs and related assets as well as a financial interest in Esperion, which will operate as a privately held, independent entity.

    Aisling Capital, Alta Partners, and Domain Associates led the financing round, which also included Arboretum Ventures. The money will go toward Esperion’s lead program for the treatment of dyslipidemias and other HDL-related therapeutics.

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Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

Do you agree that ecstasy should be studied for its potential therapeutic benefits?

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