GEN Exclusives

More »

GEN News Highlights

More »
Mar 1, 2012

Pfenex, DNA2.0 Ally to Improve Protein Expression Technology

  • Pfenex and DNA2.0 have entered an R&D agreement for genes to be expressed by Pfenex Expression Technology. DNA2.0 will develop an optimized algorithm and process for the design and synthesis of genes to be expressed in Pseudomonas fluorescens, the microorganism used in the Pfenex’ platform.

    “Pfenex is dedicated to the rapid and reliable production of high-quality recombinant proteins for our partners,” notes Bertrand Liang, M.D., CEO of Pfenex. “Through this collaboration, two industry leaders will leverage their respective capabilities to advance the Pfenex Expression Technology platform. We are very excited about this project with our long-standing gene synthesis partner, DNA2.0, because it allows us to enhance the capabilities of our technology, which will enable us to increase the overall value proposition to our partners.”

    Jeremy Minshull, Ph.D., cofounder and CEO of DNA2.0, says, “Our patented GeneGPS™ technology is based on experiment data from over-expressed synthetic genes, resulting in up to a 100-fold increase in protein expression. We have successfully optimized expression for a variety of hosts including bacteria, yeast, fungus, plant, and mammalian, and we are excited to work with Pfenex to extend our expertise to the  P. fluorescens system.”

    Pfenex is a protein production company and produces research proteins, reagent proteins, biosimilars, and innovator biopharmaceuticals. DNA2.0 offers an integrated pipeline of solutions for the research community, including gene design, optimization, synthesis, and cloning, as well as platforms for protein and strain engineering.

Add a comment

  • You must be signed in to perform this action.
    Click here to Login or Register for free.
    You will be taken back to your selected item after Login/Registration.

Related content


GEN Jobs powered by connects you directly to employers in pharma, biotech, and the life sciences. View 40 to 50 fresh job postings daily or search for employment opportunities including those in R&D, clinical research, QA/QC, biomanufacturing, and regulatory affairs.
More »

Be sure to take the GEN Poll

Patient Access to Genetic Information

Do you think patients have the absolute right to gain access to their own genetic information from medical or clinical laboratories?

More »