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Sep 14, 2009

OctoPlus Signs Contract with Axentis for Inhaled CF Therapy

  • OctoPlus signed a development and manufacturing contract with Axentis Pharma. Under terms of the deal, OctoPlus will carry out process development and clinical manufacturing of Axentis’ lead product, an inhaled liposomal formulation of tobramycin. The product, Fluidosomes™-tobramycin (also known as ARB-CF0223), is in development for the treatment of respiratory infections in cystic fibrosis patients.

    Axentis started a Phase II trial with Fluidosomes™-tobramycin in September 2008. In April 2009 the product received orphan drug designation in the U.S. for the treatment of pulmonary infections caused by Pseudomonas aeruginosa. In July FDA granted the product a second orphan drug designation or the treatment of pulmonary infections caused by Burkholderia cepacia pathogens.



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Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

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