GEN Exclusives

More »

GEN News Highlights

More »
Sep 27, 2006

Novartis Scientists Discovered Activators of PGC-1a Transcription

  • Novartis published their use of OriGene’s full-length cDNA collection to identify novel activators of PGC-1a transcription. This work was recently published in the journal Proceedings of the National Academy of Sciences titled “Transducer of regulated CREB-binding proteins (TORCs) induces PGC-1a transcription and mitochondrial biogenesis in muscle cells.”

    PGC-1a is a co-activator of PPAR-g and regulator of adaptive thermogenesis. Activators like TORCs can serve as potential therapeutic targets to modulate mitochondrial function.



Jobs

GEN Jobs powered by HireLifeScience.com connects you directly to employers in pharma, biotech, and the life sciences. View 40 to 50 fresh job postings daily or search for employment opportunities including those in R&D, clinical research, QA/QC, biomanufacturing, and regulatory affairs.
 Searching...
More »

GEN Poll

More » Poll Results »

Should “Special K” Get Special Treatment?

In the near term, what is the best way to use ketamine in treating depression?