Leading the Way in Life Science Technologies

GEN Exclusives

More »

GEN News Highlights

More »
Oct 24, 2006

New Formulation for Nexium Receives Authorization

  • AstraZeneca’s Nexium For Delayed-Release Oral Suspension has been approved for the treatment of GERD, including symptomatic gastroesophageal reflux disease, healing and maintenance of healing of erosive esophagitis, and risk reduction of NSAID-associated gastric ulcers. AstraZeneca expects that the new formulation will be available in the first quarter of 2007.

    Each packet of Nexium For Delayed-Release Oral Suspension contains either 20 mg or 40 mg of esomeprazole, the active ingredient used in Nexium Delayed-Release Capsules, explains AstraZeneca. The esomeprazole granules and inactive granules used in this formulation are mixed with water to form a suspension and are given by oral, nasogastric, or gastric administration.

    "Some patients with acid-related diseases have difficulties swallowing their oral medication when it is a solid pill," remarks Doug Levine, M.D., executive director, clinical development leader for Nexium. "This new prescription option to swallow an oral suspension of Nexium or to have it administered via a stomach tube provides these patients with an alternative method of administration that they can take instead of the Nexium capsule."



Be sure to take the GEN Poll

Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

Do you agree that ecstasy should be studied for its potential therapeutic benefits?

More »