GEN Exclusives

More »

GEN News Highlights

More »
May 14, 2010

MitoSciences Nabs $590K NIH Grant to Develop Companion Diagnostics for Antivirals

  • NIH awarded MitoSciences a $590,000 grant to support the development of companion diagnostics for antiviral drugs. The tests will be designed to help identify whether treatments for HIV, hepatitis, and other infectious diseases are likely to demonstrate mitochondrial toxicity.

    The project will be carried out in collaboration with the University of Oregon. The team will exploit MitoScience’s MitoTox™ assay technology.

    “Drug-induced mitochondrial toxicity is a problem that is receiving growing recognition,” according to Jean-Paul Audette, CEO. “A number of drugs that were removed from the market are now known to inhibit mitochondrial function.”

    MitoSciences specializes in the development of mitochondrial antibodies, mitochondrial assays, and products and services for mitochondrial-toxicity screening. The firm has generated what it claims is the world's largest collection of antimitochondrial mAbs. It has developed kits for drug discovery and toxicity studies as well as tools for the diagnosis of mitochondrial-related diseases and mitochondrial toxicity due to highly active antiretroviral therapy (HAART).

    The firm’s MitoTox™ assays are offered both as kits and also as a service through its contract research division. Work is also ongoing with clinical research partners to validate a number of the MitoTox assays for use in clinical applications including diagnostics, MitoSciences adds.

Add a comment

  • You must be signed in to perform this action.
    Click here to Login or Register for free.
    You will be taken back to your selected item after Login/Registration.

Related content


GEN Jobs powered by connects you directly to employers in pharma, biotech, and the life sciences. View 40 to 50 fresh job postings daily or search for employment opportunities including those in R&D, clinical research, QA/QC, biomanufacturing, and regulatory affairs.
More »

Be sure to take the GEN Poll

Patient Access to Genetic Information

Do you think patients have the absolute right to gain access to their own genetic information from medical or clinical laboratories?

More »