Leading the Way in Life Science Technologies

GEN Exclusives

More »

GEN News Highlights

More »
Feb 19, 2008

Merck Serono to Use Biolex’ Technology for Antibody Optimization

  • Merck Serono plans to use Biolex Therapeutics’ LEX System to evaluate antibody optimization and production. Merck Serono will investigate whether this platform has the ability to improve therapeutic profiles of its antibody candidate through optimization of antibody glycosylation structures.

    Biolex engineered the LEX System to produce antibodies with a fully human glycosylation structure without fucose. The technology also has the ability to produce antibodies that have a fully G0 glycosylation structure, lacking galactose, the company adds. These two innovations reportedly produce antibodies with greater efficacy and potency, less side effects, and reduced infusion times.



Be sure to take the GEN Poll

Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

Do you agree that ecstasy should be studied for its potential therapeutic benefits?

More »