GEN Exclusives

More »

GEN News Highlights

More »
Sep 3, 2008

Merck Serono Takes Over Full Rights to Drug Candidate for Autoimmune Disease from ZymoGenetics

  • ZymoGenetics and Merck Serono restructured existing agreements related to the development of atacicep for autoimmune diseases and research focused on inflammatory diseases.
     
    ZymoGenetics exercised its contractual right to convert to a worldwide royalty license. Hence it will no longer be responsible for funding development of atacicep. Instead, Merck Serono will fund 100% of the program costs on a worldwide basis.

    Merck Serono thus also gains exclusive, worldwide development and commercialization rights for atacicept, including in North America. Merck Serono will make milestone payments to ZymoGenetics, as agreed in the original contract between the two companies signed in 2001, and pay royalties on worldwide net sales.

    Under the revised research partnership, ZymoGenetics will now control the development and commercialization of IL-31 mAb, and Merck Serono will have the full responsibility for developing and commercializing IL-17RC. Both compounds are being evaluated for the treatment of inflammatory diseases.

    Future product candidates resulting from the companies' activities under the research alliance will be exclusively licensed for development and commercialization to either ZymoGenetics or Merck Serono.

    Merck Serono is developing atacicept (formerly referred to as TACI-Ig) as a potential treatment of autoimmune disease, such as systemic lupus erythematosus (SLE), lupus nephritis, rheumatoid arthritis, multiple sclerosis, as well as B-cell malignancies. The firm initiated a Phase II/III trial of atacicept in SLE patients  in June.



Jobs

GEN Jobs powered by HireLifeScience.com connects you directly to employers in pharma, biotech, and the life sciences. View 40 to 50 fresh job postings daily or search for employment opportunities including those in R&D, clinical research, QA/QC, biomanufacturing, and regulatory affairs.
 Searching...

Unable to get Jobs Listings.

More »

GEN Poll

More » Poll Results »

Lab-Grown Vaginas

Which body part do you think will be successfully engineered in the lab next?