Leading the Way in Life Science Technologies

GEN Exclusives

More »

GEN News Highlights

More »
Jun 18, 2008

Merck Partners with Nuevolution for Access to Chemetics Platform

  • Merck inked a drug discovery collaboration with Nuevolution to gain access to its  Chemetics® drug discovery technology. The firms will collaborate to identify small molecule leads against several drug targets of interest to Merck. Chemetics uses DNA labeling to allow fragment-based drug screening.

    Nuevolution will screen multiple multi-million member diverse fragment based screening libraries for hit identification. Through the design, synthesis, and screening of target-focused Chemetics follow-up libraries, the parties will also work together to perform hit-to-lead optimization.

    Merck will fund the research with an upfront payment to Nuevolution and will make milestone payments as candidate molecules progress through preclinical and clinical development and onto the market. Additionally, Nuevolution is eligible to receive royalties on the commercial sales of approved products.

    Related Links:

    Nuevolution Announces Drug Discovery Alliance With Lexicon Pharmaceuticals

    Fragment-Based Approach Increases Leads



Be sure to take the GEN Poll

Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

Do you agree that ecstasy should be studied for its potential therapeutic benefits?

More »