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Apr 23, 2007

KaloBios Licenses Humaneering Technology to Novartis

  • KaloBios Pharmaceuticals’ granted Novartis a nonexclusive license its Humaneering™ technology. Novartis will use the platform to develop human antibodies.

    This is the first such nonexclusive technology transfer that KaloBios has offered for its Humaneering platform. As part of the transition plan, KaloBios has agreed to Humaneer three antibodies for Novartis in addition to the three that have been successfully completed as part of a pilot R&D relationship.

    "This nonexclusive license brings in sufficient new revenue to fund our clinical studies for KB001 (Pseudomonas infections) and our three clinical programs for KB002 (inflammation and autoimmune indications) into mid 2008," notes David Pritchard, KaloBios CEO.

    Humaneering is KaloBios’ method for converting nonhuman antibodies into engineered human antibodies for therapeutic drug applications. The system maintains epitope specificity and increases affinity, according to the company. The Humaneered antibodies are as close as, if not closer to, human germline sequences than the products of fully human antibody generation techniques.

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Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

Do you agree that ecstasy should be studied for its potential therapeutic benefits?

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