Introgen Technical Services
(ITS) inked agreements to manufacture biological materials for Advantagene
and the H. Lee Moffitt Cancer Center
. Additionally, the company expanded its collaboration with Oncolys
BioPharma. Aggregate proceeds to ITS from these contracts total more than $1 million.
ITS will complete additional GMP production services related to Oncolys’ cancer drug candidate. Telomelysin® is an adenovirus type 5 vector carrying the human telomerase reverse transcriptase (hTERT) gene. It is being studied in Phase I trials for the treatment of head and neck cancers, hepatocellular carcinoma, and esophageal cancer.
ITS will also manufacture Advantagene’s ProstAtak™, an adenovirus type 5 vector carrying the herpes simplex thymidine kinase gene. This product is being evaluated in Phase II as a treatment for prostate cancer.
Additionally, the company will produce H. Lee Moffitt’s adenovirus type 5 vector carrying a gene for Survivin protein production. This compound has potential applications in the treatment of small-cell lung cancer.
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