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Jan 17, 2007

Insert Signs Deal Related to R&D-Biopharmaceuticals’ Anticancer Agent

  • Insert Therapeutics and R&D-Biopharmaceuticals will develop and commercialize conjugates of the anticancer compound tubulysin with Insert’s drug delivery system, Cyclosert™. Tubulysins are naturally occurring cytotoxins that prevent cell growth and division by destabilizing microtubules.

    R&D will supply Insert with tubulysin technology and material. The two companies will work jointly on the synthesis of the conjugate, after which, Insert will perform the preclinical testing.

    The agreement includes an upfront fee to R&D, funding from Insert for R&D’s research, milestone payments on clinical development and approvals, and royalties on product sales. It also provides a research license and an option for an exclusive license to develop and commercialize tubulysin-polymer conjugates.



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Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

Do you agree that ecstasy should be studied for its potential therapeutic benefits?

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