GEN Exclusives

More »

GEN News Highlights

More »
Jan 2, 2007

Hematech Produces Healthy Prion Protein-Knockout Cows

  • Hematech reported the production of healthy prion protein-knockout cows. The companies suggest that such healthy prion protein-free calves should be useful in investigating the function of normal cellular prion protein and the nature of prion diseases in humans and animals. Additionally, the cows will act as a source of prion protein-free products. 

    "By knocking out the prion protein gene and producing healthy calves, our team has successfully demonstrated that normal cellular prion protein is not necessary for the normal development and survival of cattle,” states M. Robl, Ph.D., president and CSO of Hematech. “The cows are now nearly two years old and are completely healthy."

    Hematech is developing a bovine system for production of human polyclonal antibodies. As part of this effort, a gene targeting system was developed. This system was used to produce the prion protein-knockout calves. Hemacure conducted this work in collaboration with Kirin Brewery Company and published the data in Nature Biotechnology.


GEN Jobs powered by connects you directly to employers in pharma, biotech, and the life sciences. View 40 to 50 fresh job postings daily or search for employment opportunities including those in R&D, clinical research, QA/QC, biomanufacturing, and regulatory affairs.
More »

Be sure to take the GEN Poll

The Triple Package and Success

One theory for explaining “success," put forward by Amy Chua Jed Rubenfeld, posits cultural traits such as a superiority complex, personal insecurity and impulse control. Union College professors Joshua Hart and Christopher Chabris counter that intelligence, conscientiousness, and economic advantage are the most likely elements of success, regardless of ethnicity. Do you think that Hart-Chabris make a better argument for achieving success than the Chua-Rubenfeld theory?

More »