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Mar 3, 2010

GSK to Use Gentronix’ GreenScreen HC and BlueScreen HC Genotoxicity Assays

  • Gentronix entered into a three-year agreement to provide GlaxoSmithKline (GSK) with GreenScreen HC and BlueScreen HC genotoxicity assays. The reporter-based assays have demonstrated the ability to detect known classes of genotoxic agent and utilize Green Fluorescent Protein or Gaussia Luciferase to detect GADD-45a upregulation, which is a key indicator of DNA damage.

    GreenScreen HC is a human cell-based assay technology that combines high sensitivity for detecting genotoxic chemicals with high specificity for reducing false positive results, Gentronix notes. BlueScreen HC is the new luciferase-based assay that combines all the attributes of GreenScreen HC with the ability to be run in a 384-well microtiter plate format.



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Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

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