Leading the Way in Life Science Technologies

GEN Exclusives

More »

GEN News Highlights

More »
Sep 21, 2009

Enzo Teams Up with NIH National Eye Institute for Clinical Trial with Optiquel

  • Enzo Biochem signed a cooperative R&D agreement with the NIH’s National Eye Institute, centered on carrying out a proof-of-concept clinical trial of Optiquel™, Enzo’s oral therapeutic for chronic autoimmune uveitis.

    Enzo will supply the compound and fund a portion of the studies. The agreement with the National Eye Institute also covers nonclinical research into the use of compounds to enhance the immune-mediated oral tolerance response to specific antigens.

    Enzo says that this work may have applications across its whole immune regulation platform including its Crohn’s disease candidate, Alequel™, and EGS21™, which is in development for treating nonalcoholic steatohepatitis. Enzo most recently reported positive results from a Phase II trial with Alequel in patients with moderate-to-severe Crohn’s disease.

     



Related content

Be sure to take the GEN Poll

Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

Do you agree that ecstasy should be studied for its potential therapeutic benefits?

More »