GEN Exclusives

More »

GEN News Highlights

More »
Apr 17, 2012

Eclipse Therapeutics Gains Rights to Preclinical Oncology Antibodies from Dyax

  • Dyax has granted Eclipse Therapeutics an exclusive, worldwide license to preclinical oncology candidates. The deal covers development and commercialization of compounds that target cancer stem cells. In exchange, Dyax will receive an initial license fee, payments upon the achievement of clinical development and sales milestones, and royalties on worldwide net sales resulting from commercialized products.

    “This agreement further underscores the significant long-term potential of our robust licensing and funded research program, which continues to be a key driver of near- and long-term value creation for Dyax with 18 therapeutic candidates currently in the clinic, including four in Phase III and four in Phase II,” states Gustav A. Christensen, president and CEO of Dyax. The company also has one product on the market. Ecallantide, approved under the brand name Kalbitor in the U.S., is indicated for the treatment of acute attacks of hereditary angioedema in patients 16 years of age and older.

    Peter Chu, Ph.D., president and co-founder of Eclipse, remarks, “This agreement provides Eclipse with multiple high-value antibody candidates targeting cancer stem cells developed using Eclipse’s unique CSC Rx Discovery™ platform and Dyax’ proven phage display technology. Our oncology pipeline focuses on identifying functional therapeutics that specifically inhibit CSC targets critical to the maintenance of cancer stem cells at the root of cancer."

Add a comment

  • You must be signed in to perform this action.
    Click here to Login or Register for free.
    You will be taken back to your selected item after Login/Registration.

Related content


GEN Jobs powered by connects you directly to employers in pharma, biotech, and the life sciences. View 40 to 50 fresh job postings daily or search for employment opportunities including those in R&D, clinical research, QA/QC, biomanufacturing, and regulatory affairs.
More »

Be sure to take the GEN Poll

Patient Access to Genetic Information

Do you think patients have the absolute right to gain access to their own genetic information from medical or clinical laboratories?

More »