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Jan 4, 2007

Coda and Integrated Genomics Collaborate on Pichia Yeast Expression Systems

  • Coda Genomics and Integrated Genomics entered into a collaboration to apply Coda’s Translation Engineering™ protein expression technology to the Pichia yeast expression system.

    Robert J. Molinari, Ph.D., CEO of Coda, points out that translation engineering technologies address protein expression, solubility, and activity challenges in rational design steps at all stages of pharmaceutical development. “This utilization of synthetic biology can change the competitive landscape of many businesses, which rely on successful protein production,” he notes.

    Integrated Genomics will provide the detailed genomic sequence of Pichia and other cell lines used in protein production. “The accurate sequence, assembly, and detailed annotation provided by Integrated Genomics allows Coda to provide enhanced genes for protein expression without amino acid changes in proteins of interest,” explains John Elling, Ph.D., president of Integrated Genomics.



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Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

Do you agree that ecstasy should be studied for its potential therapeutic benefits?

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