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Jan 5, 2011

AstraZeneca Turns to Kinaxo to Study PTMs Related to an Oncology Program

  • AstraZeneca and Kinaxo have entered into an agreement in which Kinaxo will employ its high-end mass spectrometry-based technologies to quantitatively analyze post-translational modifications (PTMs) in proteins on a proteome-wide scale in support of one of AstraZeneca’s oncology programs.

    Kinaxo’s Cellular Target Profiling technology employs a combination of quantitative mass spectrometry and software applications to analyze proteome-wide PTM patterns in vivo. The platform provides insights into small molecule target interactions and binding affinities across the proteome of any given cell line or tissue sample, according to the firm. In addition, the compound’s protein targets are determined in a physiological context.



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Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

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