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Oct 17, 2006

Astex Receive Patents Covering the Use of Human Cytochrome P450 Structures

  • Astex Therapeutics was granted two patents covering the use of the crystal structures of human cytochrome P450 enzymes. Cytochrome P450 are proteins involved in the body's break-down of drug products and are used in pharmaceutical R&D.

    “Insights provided by the crystal structures of human cytochrome P450 enzymes help pharmaceutical researchers to design safer and more effective new medicines," points out Leon Bushara, CEO. "Astex scientists were the first to solve these structures and publish them.”

    The two patents awarded to Astex are European patent EP1 438 337(1) covering the use of the crystal structure of human cytochrome P450 2C9 and GB 2 408 609(2) which covers the use of the crystal structure of human cytochrome P450 3A4.



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Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

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