Alnylam Pharmaceuticals and Max Planck Institute of Molecular Cell Biology and Genetics are working together to understand the molecular mechanisms behind intracellular transport of siRNA.
Under the exclusive research agreement, Alnylam scientists will work closely with the laboratory of Marino Zerial, Ph.D., to investigate cellular uptake pathways in a high-throughput manner. Alnylam will have an option on any resulting intellectual property.
“Through this collaboration,” notes Marino Zerial, Ph.D., research group leader and director at the Max Planck Institute of Molecular Cell Biology and Genetics, “we will increase our understanding of how different siRNA formulations are internalized within cells and then use this knowledge to further optimize approaches for delivery of RNAi therapeutics.”