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Mar 11, 2008

Ace BioSciences Allies with PATH on Temperature-Stable Diarrhea Vaccines

  • Ace BioSciences will aid PATH in its efforts to create a vaccine against bacterial diarrhea for the developing world. The focus will be on developing temperature-stable ETEC (enterotoxigenic E. Coli) vaccine formulations.

    Funding for the research will come from PATH’s Enteric Vaccine Initiative. Ace Biosciences will collaborate with PATH’s Vaccine Stabilization Project team to develop dry and temperature-stable ETEC vaccine candidates.

    The pilot studies will use Ace BioSciences’ live, whole-cell oral vaccine candidate. ACE527, which the company is developing as a vaccine for traveller’s diarrhea, comprises three attenuated ETEC strains. Ace Biosciences reports that five Phase I trials have demonstrated safety and immunogenicity.



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Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

Do you agree that ecstasy should be studied for its potential therapeutic benefits?

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