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August 25, 2014

No Evidence for Circulating Mesenchymal Stem Cells in Patients with Organ Injury

This recent study sheds light on a contested issue.

No Evidence for Circulating Mesenchymal Stem Cells in Patients with Organ Injury

The theory that MSCs are released from the bone marrow into the bloodstream following organ damage has long been debated. [© krishnacreations - Fotolia.com]

Abstract
Mesenchymal stem cells (MSC) are present in the bone marrow, from where they are thought to migrate via the blood stream to sites of injury However, virtually all tissues contain resident MSC that may contribute to local regenerative and immunomodulatory processes, thereby hypothetically pre-empting the need for recruiting MSC via ...

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