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May 22, 2014

Literature Review: Getting to the Core

This literature review describes a study where researchers used 3D high-content screening to identify compounds that target cells in inner MCTS core regions.

Literature Review: Getting to the Core

Substances that target cancer cells in poorly vascularized tumor regions have the potential to enhance cytostatic-based chemotherapy of solid tumors. [© freshidea - Fotolia.com]

Cells within a tumor experience very different microenvironments depending on whether they are on the periphery or at the core of the tumor This is due in part to the differing distance from the blood vessels that supply oxygen and nutrients to the tumors There is a gradient of oxygen, ...

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